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, This year). Prolonged Discussion NMR solution framework results contrast along with fixed crystal structures involving paromomycin, gentamicin and also apramycin bound to the same RNA oligonucleotide, that demonstrate a new de-stacked conformation of A1492 along with A1493 (Han et?al., June 2006). The actual crystal structure of the apramycin-RNA complicated might cause 23 NOE transgression (>0.

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