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These studies typically had a limited number of sampling time points and used clopidogrel LDs of ��600 mg. A few studies evaluated the efficacy and the good tolerance of higher clopidogrel LDs before PCI (6, 7?and?14), confirming a dose-effect relationship with apparently no saturation point in absorption or metabolization, at least to LDs of clopidogrel as high as 900 mg (14). To address the ques

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